Emiliano Santarnecchi

Research Interests:

Emiliano Santarnecchi is an Associate Professor of Radiology at Harvard Medical School (HMS), and the director of the Precision Neuroscience & Neuromodulation program (PNN) and the Network Control Laboratory at the Gordon Center for Medical Imaging at Massachusetts General Hospital (MGH). 

Dr. Santarnecchi’s program focuses on combining multimodal neuroimaging (e.g., MRI, fMRI, DTI, PET) and electrophysiology (e.g., EEG, EMG, MEG) methods for the identification of novel biomarkers and the development of therapeutic approaches for patients with neurological and psychiatric conditions. In particular, Dr. Santarnecchi’s research is centered around the development of personalized, network-based Noninvasive Brain Stimulation (NiBS) approaches to modulate brain plasticity, guide connectome rewiring and enhance cognitive function, with the ultimate goal of promoting Brain Health and healthy Aging. His team is currently working on machine learning and AI-based solutions for perturbation-based brain connectivity analysis (TMS-EEG, fMRI), NIBS approaches to modulate sleep and memory, high-frequency transcranial electrical stimulation interventions for the treatment of Alzheimer’s disease and Frontotemporal dementia, and novel fMRI markers of disease progression in patients with brain tumors.