Emiliano Santarnecchi, PhD
Read BioEmiliano Santarnecchi is an Associate Professor of Radiology at Harvard Medical School (HMS), and the director of the Precision Neuroscience & Neuromodulation program (PNN) and the Network Control Laboratory at the Gordon Center for Medical Imaging at Massachusetts General Hospital (MGH).
Dr. Santarnecchi’s program focuses on combining multimodal neuroimaging (e.g., MRI, fMRI, DTI, PET) and electrophysiology (e.g., EEG, EMG, MEG) methods for the identification of novel biomarkers and the development of therapeutic approaches for patients with neurological and psychiatric conditions. In particular, Dr. Santarnecchi’s research is centered around the development of personalized, network-based Noninvasive Brain Stimulation (NiBS) approaches to modulate brain plasticity, guide connectome rewiring and enhance cognitive function, with the ultimate goal of promoting Brain Health and healthy Aging. His team is currently working on machine learning and AI-based solutions for perturbation-based brain connectivity analysis (TMS-EEG, fMRI), NIBS approaches to modulate sleep and memory, high-frequency transcranial electrical stimulation interventions for the treatment of Alzheimer’s disease and Frontotemporal dementia, and novel fMRI markers of disease progression in patients with brain tumors.
Recent Publications
Smeralda CL, Pandit S, Turrini S, Reilly J, Palmisano A, Sprugnoli G, Hampel H, Benussi A, Borroni B, Press D, Rotenberg A, El Fakhri G, Koch G, Rossi S, Santarnecchi E The role of parvalbumin interneuron dysfunction across neurodegenerative dementias. Ageing Res Rev. 2024;101:102509 - PMID: 39306248 - DOI: 10.1016/j.arr.2024.102509
Demchenko I, Rampersad S, Datta A, Horn A, Churchill NW, Kennedy SH, Krishnan S, Rueda A, Schweizer TA, Griffiths JD, Boyden ES, Santarnecchi E, Bhat V Target engagement of the subgenual anterior cingulate cortex with transcranial temporal interference stimulation in major depressive disorder: a protocol for a randomized sham-controlled trial. Front Neurosci. 2024;18:1390250 - PMID: 39268031 - PMCID: PMC11390435 - DOI: 10.3389/fnins.2024.1390250
Mendes Zambetta R, Signini ÉF, Ocamoto GN, Catai AM, Uliam NR, Santarnecchi E, Russo TL Effects of weightlessness on the cardiovascular system: a systematic review and meta-analysis. Front Physiol. 2024;15:1438089 - PMID: 39129756 - PMCID: PMC11310543 - DOI: 10.3389/fphys.2024.1438089
Benelli A, Memoli C, Neri F, Romanella SM, Cinti A, Giannotta A, Lomi F, Scoccia A, Pandit S, Zambetta RM, Rossi S, Santarnecchi E Reduction of cognitive fatigue and improved performance at a VR-based driving simulator using tRNS. iScience. 2024;27(9):110536 - PMID: 39314236 - PMCID: PMC11418143 - DOI: 10.1016/j.isci.2024.110536
Mencarelli L, Torso M, Borghi I, Assogna M, Pezzopane V, Bonnì S, Di Lorenzo F, Santarnecchi E, Giove F, Martorana A, Bozzali M, Ridgway GR, Chance SA, Koch G Macro and micro structural preservation of grey matter integrity after 24 weeks of rTMS in Alzheimer's disease patients: a pilot study. Alzheimers Res Ther. 2024;16(1):152 - PMID: 38970141 - PMCID: PMC11225141 - DOI: 10.1186/s13195-024-01501-z
- More publications ...
