Our overall goal is to serve the clinical and research PET/MR communities by providing access to state-of-the art PET/MR technology both on the software side (quantitation and reconstruction methods, kinetic modeling tools) as well as the hardware/radiochemistry versant (micro-coils, dual PET-MR probes).

Our service activities can be described in three categories: 1) Regional service that enables clinical and pre-clinical PET/MR research; 2) On-site service that enables the deployment of specific software and radiopharmaceuticals using physical resources such as radiopharmacy labs, PET/MR scanner, supercomputers with very large flat physical memory; and 3) Electronic support for research using the electronically downloadable software that will be developed for motion, attenuation and PSF quantitation, PET/MR reconstruction, kinetic modeling, etc.

Service Project TitleService Project Partner InteractionInstitution/DepartmentService partner Funding # Period of Funding
Targeting Choline Phospholipid Metabolism in LymphangioleiomyomatosisCarmen Priolo* (TR&D 3)Brigham & Women’s Hospital Medicine, Pulmonary & Critical CareR01HL130336 12/2015 – 11/2021
  Neurobiological underpinnings of placebo response in depressionMaurizio Fava Cristina Cusin* Diego Pizzagalli (TR&D 1,2,3)McLean Hospital; Massachusetts General Hospital Psychiatry  R01MH102279 6/2015 – 6/2021
Exploiting Ferroportin for Cancer Imaging and TherapyJan Grimm  (TR&D 3)Memorial Sloan Kettering Nuclear MedicineR01CA218615 6/2017 – 6/2022
Football Players Health’s Study at HarvardRoss Zafonte (TR&D 1,2,3)Spaulding Rehabilitation Network Physical Medicine & RehabilitationFootball Player Association  6/2016 – 6/2022    
 Ravinder Ragetti (TR&D 1,2)NYU Langone Health Radiology   
Ultra-high resolution brain PET scanner for in-vivo autoradiography imagingRoger Lecomte (TR&D 1,2,3)University of Sherbrooke Nuclear Medicine & RadiobiologyU01EB027003 9/2018 – 6/2023
Assessment of Glutamatergic Neurosystem in Fragile X Syndrome for Targeted TherapyAnna-Liisa Brownell* (TR&D 1,2,3)Massachusetts General Hospital RadiologyCDMRP – W81XWH-17-1-0228 6/2017 – 6/2021
Imaging Tau, Amyloid, and Neurodegeneration in PPABradford Dickerson (TR&D 1,2,3)Massachusetts General Hospital NeurologyR01DC014296 9/2016 – 8/2021
Improving early disease detection and imaging with MRI nanotechnologyZdenka Kuncic* (TR&D 3)University of Sydney Institute of Nanoscale Science and Technology  Australian Academy of Technology and Engineering  (ASTE) 6/2018 – 6/2020
PET/MR mapping of myocardial membrane potentialGeorges El Fakhri (TR&D 1,2)Massachusetts General Hospital RadiologyR01HL137230 9/2017 – 6/2022
Motion-Compensated Simultaneous MRI and PET ImagingRoger Fulton (TR&D 1,2)University of Sydney / Brain & Mind InstituteAustralian Research Council (ARC)