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Publications

2016
  • Beucke JC, Sepulcre J, Buhlmann U, Kathmann N, Moody T, Feusner JD. Degree connectivity in body dysmorphic disorder and relationships with obsessive and compulsive symptoms. Eur Neuropsychopharmacol 2016
  • Ortiz-Teran L, Ortiz T, Perez DL, Aragon JI, Diez I, Pascual-Leone A, Sepulcre J. Brain Plasticity in Blind Subjects Centralizes Beyond the Modal Cortices. Front Syst Neurosci 2016; 10():61
  • Sepulcre J, Schultz AP, Sabuncu M, Gomez-Isla T, Chhatwal J, Becker A, Sperling R, Johnson KA. In Vivo Tau, Amyloid, and Gray Matter Profiles in the Aging Brain. J. Neurosci. 2016; 36(28):7364-74
  • Teipel S, Grothe MJ, Zhou J, Sepulcre J, Dyrba M, Sorg C, Babiloni C. Measuring Cortical Connectivity in Alzheimer's Disease as a Brain Neural Network Pathology: Toward Clinical Applications. J Int Neuropsychol Soc 2016; 22(2):138-63
  • Johnson KA, Schultz A, Betensky RA, Becker JA, Sepulcre J, Rentz D, Mormino E, Chhatwal J, Amariglio R, Papp K, Marshall G, Albers M, Mauro S, Pepin L, Alverio J, Judge K, Philiossaint M, Shoup T, Yokell D, Dickerson B, Gomez-Isla T, Hyman B, Vasdev N, Sperling R. Tau positron emission tomographic imaging in aging and early Alzheimer disease. Ann. Neurol. 2016; 79(1):110-9
  • Hu C, Sepulcre J, Johnson KA, Fakhri GE, Lu YM, Li Q. Matched signal detection on graphs: Theory and application to brain imaging data classification. Neuroimage 2016; 125():587-600
  • Sepulcre J, Masdeu JC. Advanced Neuroimaging Methods Towards Characterization of Early Stages of Alzheimer's Disease. Methods Mol. Biol. 2016; 1303():509-19
2015
  • Abad E, Sepulcre J, Martinez-Lapiscina EH, Zubizarreta I, Garcia-Ojalvo J, Villoslada P. The analysis of semantic networks in multiple sclerosis identifies preferential damage of long-range connectivity. Mult Scler Relat Disord 2015; 4(5):387-94
  • Hu C, Cheng L, Sepulcre J, Johnson KA, Fakhri GE, Lu YM, Li Q. A spectral graph regression model for learning brain connectivity of Alzheimer's disease. PLoS ONE 2015; 10(5):e0128136
  • Carmona S, Hoekzema E, Castellanos FX, Garcia-Garcia D, Lage-Castellanos A, Van Dijk KR, Navas-Sanchez FJ, Martinez K, Desco M, Sepulcre J. Sensation-to-cognition cortical streams in attention-deficit/hyperactivity disorder. Hum Brain Mapp 2015; 36(7):2544-57
  • Sepulcre J. An OP4 functional stream in the language-related neuroarchitecture. Cereb. Cortex 2015; 25(3):658-66
2014
  • Sepulcre J. Functional streams and cortical integration in the human brain. Neuroscientist. 2014 Oct; 20(5):499-508.
  • Sepulcre J. Integration of visual and motor functional streams in the human brain. Neuroscience Letters. 2014 May 1; 567:68-73.
  • Beucke JC, Sepulcre J, Eldaief MC, Sebold M, Kathmann N, Kaufmann C. Default mode network subsystem alterations in obsessive-compulsive disorder. Br J Psychiatry. 2014 Nov;205(5):376-82.
2013
  • Sepulcre J. An OP4 Functional Stream in the Language-Related Neuroarchitecture. Cerebral Cortex. 2013 Oct 17.
  • Johnson KA, Sperling RA, Sepulcre J. Functional connectivity in Alzheimer's disease: measurement and meaning. Biological Psychiatry. 2013 Sep 1;74(5):318-9.
  • Sepulcre J, Sabuncu MR, Becker A, Sperling R, Johnson KA. In vivo characterization of the early states of the amyloid-beta network. Brain. 2013 Jul;136(Pt 7):2239-52.
  • Beucke JC, Sepulcre J, Talukdar T, Linnman C, Zschenderlein K, Endrass T, Kaufmann C, Kathmann N. Abnormally high degree connectivity of the orbitofrontal cortex in obsessive-compulsive disorder. JAMA Psychiatry. 2013 Jun;70(6):619-29.
  • Mueller S, Wang D, Fox MD, Yeo BT, Sepulcre J, Sabuncu MR, Shafee R, Lu J, Liu H. Individual variability in functional connectivity architecture of the human brain. Neuron. 2013 Feb 6;77(3):586-95.
  • Spreng RN, Sepulcre J, Turner GR, Stevens WD, Schacter DL. Intrinsic architecture underlying the relations among the default, dorsal attention, and frontoparietal control networks of the human brain. Journal of Cognitive Neuroscience. 2013 Jan;25(1):74-86.
  • Hu C, Cheng L, Sepulcre J, El Fakhri G, Lu YM, Lu YM. Matched signal detection on graphs: theory and application to brain network classification. Inf Process Med Imaging. 2013;23:1-12.
2012
  • Sepulcre J, Sabuncu MR, Johnson KA. Network assemblies in the functional brain. Curr Opin Neurol. 2012 Aug; 25(4):384-91.
  • Sepulcre J, Sabuncu MR, Yeo TB, Liu H, Johnson KA. Stepwise connectivity of the modal cortex reveals the multimodal organization of the human brain. J Neurosci. 2012 Aug 1; 32(31):10649-61.
2011
  • Sepulcre J, Peraita H, Goni J, Arrondo G, Martincorena I, Duque B, Velez de Mendizabal N, Masdeu JC, Villoslada P. Lexical access changes in patients with multiple sclerosis: a two-year follow-up study. Journal of Clinical and Experimental Neuropsychology. 2011 Feb;33(2):169-75.
  • Goni J, Arrondo G, Sepulcre J, Martincorena I, Velez de Mendizabal N, Corominas-Murtra B, Bejarano B, Ardanza-Trevijano S, Peraita H, Wall DP, Villoslada P. The semantic organization of the animal category: evidence from semantic verbal fluency and network theory. Cognitive Processing. 2011 May;12(2):183-96.
  • Stufflebeam SM, Liu H, Sepulcre J, Tanaka N, Buckner RL, Madsen JR. Localization of focal epileptic discharges using functional connectivity magnetic resonance imaging. Journal of Neurosurgery. 2011 Jun;114(6):1693-7.
  • Drzezga A, Becker JA, Van Dijk KR, Sreenivasan A, Talukdar T, Sullivan C, Schultz AP, Sepulcre J, Putcha D, Greve D, Johnson KA, Sperling RA. Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden. Brain. 2011 Jun;134(Pt 6):1635-46.
  • Bejarano B, Bianco M, Gonzalez-Moron D, Sepulcre J, Goni J, Arcocha J, Soto O, Del Carro U, Comi G, Leocani L, Villoslada P. Computational classifiers for predicting the short-term course of Multiple sclerosis. BMC Neurology. 2011 Jun 7;11:67.
  • Yeo BT, Krienen FM, Sepulcre J, Sabuncu MR, Lashkari D, Hollinshead M, Roffman JL, Smoller JW, Zollei L, Polimeni JR, Fischl B, Liu H, Buckner RL. The Organization of the Human Cerebral Cortex Estimated By Functional Connectivity. Journal of Neurophysiology. 2011 Jun 8.
  • Velez de Mendizabal N, Carneiro J, Sole RV, Goni J, Bragard J, Martinez-Forero I, Martinez-Pasamar S, Sepulcre J, Torrealdea J, Bagnato F, Garcia-Ojalvo J, Villoslada P. Modeling the effector - regulatory T cell cross-regulation reveals the intrinsic character of relapses in Multiple Sclerosis. BMC System Biology. 2011 Jul 15;5:114.
  • Sabuncu MR, Desikan RS, Sepulcre J, Yeo BT, Liu H, Schmansky NJ, Reuter M, Weiner MW, Buckner RL, Sperling RA, Fischl B; for the Alzheimer's Disease Neuroimaging Initiative. The Dynamics of Cortical and Hippocampal Atrophy in Alzheimer Disease. Archives of Neurology. 2011 Aug;68(8):1040-1048.
2010
  • Sepulcre J, Liu H, Talukdar T, Martincorena I, Yeo BT, Buckner RL. The organization of local and distant functional connectivity in the human brain. PLoS Comput Biol. 2010 Jun; 6(6):e1000808.
  • Andrews-Hanna J, Reidler JS, Sepulcre J, Poulin R, Buckner RL. Functional-anatomic fractionation of the brain’s default network. Neuron, 2010, 25;65(4):550-62.
2009
  • Sepulcre J, Masdeu J, Goni J, Velez de Mendizabal N, Barbosa C, Pastor A, Villoslada P. Brain pathways of verbal working memory: A lesion-function correlation study. Neuroimage. 2009, 15;47(2):773-8.
  • Arrondo G, Alegre M, Sepulcre J, Iriarte J, Artieda J, Villoslada P. Abnormalities in brain synchronization are correlated with cognitive impairment in multiple sclerosis. Multiple Sclerosis. 2009, 15(4):509-16.
  • Sepulcre J, Goni J, Bejarano B, Velez de Mendizabal N, Toledo JB, Masdeu JC, Villoslada P. Contribution of axonal damage to grey matter atrophy in multiple sclerosis. Evidence from voxel-based analysis of T1 lesions in the visual pathway. Archives of Neurology. 2009, 66(2):173-179.
  • Buckner RL, Sepulcre J, Talukdak T, Krienen F, Liu H, Hedden T, Andrews-Hanna J, Sperling RA, Johnson KA. Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer’s disease. Journal of Neuroscience. 2009, 11;29(6):1860-73.
  • Esteban FJ, Sepulcre J, Ruiz de Miras J, Navas J, Velez de Mendizabal N, Goni J, Quesada JM, Bejarano B, Villoslada P. Fractal dimension analysis of grey matter in multiple sclerosis. Journal of the Neurological Sciences. 2009, 15;282(1-2):67-71.
  • Sepulcre J, Masdeu JC, Goni J, Arrondo G, Velez de Mendizabal N, Bejarano B, Villoslada P. Fatigue in multiple sclerosis is associated with the disruption of attentional networks. Multiple Sclerosis. 2009, 15(3):337-44.
  • Villoslada P, Arrondo G, Sepulcre J, Alegre M, Artieda J. Memantine induces transient and reversible neurological impairment in patients with MS. Neurology. 2009, 12;72(19):1630-3.
2008
  • Sepulcre J, Masdeu JC, Sastre-Garriga J, Goni J, Velez-de-Mendizabal N, Duque B, Pastor MA, Bejarano B, Villoslada P. Mapping the brain pathways of declarative verbal memory. Evidence from white matter lesions in the living human brain. Neuroimage. 2008, 1;42(3):1237-43.
  • Sepulcre J, Masdeu JC, Palacios R, Goni J, Moreno B, Tainta M, Bejarano B, Villoslada P. HLA-DR2 and white matter lesions distribution in MS. Journal of Neuroimaging. 2008, 18(3):328-31.
  • Villoslada P, Sepulcre J, Toledo J, Bejarano B. Retinal nerve fiber layer is associated with brain atrophy in multiple sclerosis. Neurology. 2008, 71(21):1747-8.
  • Martinez-Forero I, Garcia-Munoz R, Martinez-Pasamar S, Inoges S, Lopez-Diaz de Cerio A, Palacios R, Sepulcre J, Moreno B, Gonzalez Z, Fernandez-Diez B, Melero I, Bendandi M, Villoslada P. IL-10 suppressor activity and ex vivo Tr1 cell function are impaired in multiple sclerosis. European Journal of Immunology. 2008, 38(2):576-86.
  • Pampliega O, Domercq M, Villoslada P, Sepulcre J, Rodriguez-Antiguedad A, Matute C. Association of an EAAT2 polymorphism with higher glutamate concentration in relapsing multiple sclerosis. Journal of Neuroimmunology. 2008, 195(1-2):194-8.
  • Goni J, Esteban FJ, Velez de Mendizabal N, Sepulcre J, Agirrezabal I, Ardanza-Trevijano S, Villoslada P. A computational analysis of the protein-protein interaction networks in neurodegenerative diseases. BMC Systems Biology. 2008, 20;2(1):52.
  • Duque B, Sepulcre J, Bejarano B, Villoslada P. Verbal memory declines steadily from the early phase of MS and independently of disease activity. Multiple Sclerosis. 2008, 14(7):947-53.
  • Toledo J, Sepulcre J, Salinas-Alaman A, Garcia-Layana A, Murie M, Bejarano B, Villoslada P. Retinal nerve fiber layer atrophy is associated with physical and cognitive disability in multiple sclerosis. Multiple Sclerosis. 2008, 14(7):906-12.
2007
  • Sepulcre J, Murie-Fernandez M, Salinas-Alaman A, Garcia-Layana A, Bejarano B, Villoslada P. Diagnostic Accuracy of Retinal Nerve Fiber Layer Thickness measurement and retinal periphlebitis presence in predicting disease activity in multiple sclerosis. Neurology. 2007, 1;68(18):1488-94
  • Riverol M, Sepulcre J, Fernandez-Alonso M, Uccelli A, Brieva L, Rubio M, Rodriguez A, Fernandez-Diez B, Villoslada P. Antibodies against Epstein-Barr virus and herpesvirus type 6 are associated with the early phases of multiple sclerosis. Journal of Neuroimmunology. 2007, 192(1-2):184-5.
  • Esteban FJ, Sepulcre J, Velez de Mendizabal N, Goni J, Navas J, Ruiz de Miras J, Bejarano B, Masdeu JC, Villoslada P. Fractal dimension and white-matter changes in multiple sclerosis. Neuroimage. 2007, 1;36(3):543-9.
  • Palacios R, Goni J, Martinez I, Iranzo J, Sepulcre J, Melero I, Villoslada P. A Network analysis of the human T-cell activation gene network identifies Jagged1 as a therapeutic target for autoimmune diseases. PLoS ONE. 2007, 21;2(11):e1222.
2006
  • Sepulcre J, Vanotti S, Hernandez R, Sandoval G, Caceres F, Garcea O, Villoslada P. Cognitive impairment in patients with MS using the Brief Repeatable Battery-Neuropsychology Test. Multiple Sclerosis. 2006, 12: 187-195.
  • Sepulcre J, Sastre-Garriga J, Cercignani M, Ingle GT, Miller DH, Thompson AJ. Regional grey matter atrophy in early primary progressive MS: a voxel-based morphometry study. Archives of Neurology. 2006, 63(8):1175-80.
  • Moreno B, Hevia H, Santamaria M, Sepulcre J, Munoz J, Garcia-Trevijano ER, Berasain C, Corrales FJ, Avila MA, Villoslada P. Methylthioadenosine reverses brain autoimmune disease. Annals of Neurology. 2006, 60(3):323-34.