Quantitative Simultaneous PET-MR Imaging

The goals of this research are to develop novel quantitative methods for simultaneous whole-body (WB) PET-MR imaging, validate these methods in animal models and evaluate their clinical value, compared to PET-CT, in monitoring response to cancer therapy. Simultaneous PET-MR is a novel and promising imaging modality that is generating substantial interest in the medical community and offers the scientific community many challenges and opportunities. Unlike sequentially-acquired WB PET-CT scans, the simultaneous acquisition of MR and PET data can be used to incorporate MR information into the PET reconstruction model. We hypothesize that the additional MR information will yield substantial improvement of PET in terms of lesion detection and activity estimation.

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