Woo Lab

About the lab

PI: Jonghye Woo

The Woo lab focuses on novel development of theoretical and computational methods for image analysis that infer useful information from a variety of medical imaging data. We are particularly interested in novel development of (1) instrumentation to capture motion and structure of organs, (2) multimodal data integration (e.g., multimodal registration) through multimodal atlases to understand the relationship between anatomy and function, and (3) data mining (e.g., deep learning) to investigate underlying mechanisms of motion/physiology.

Research

• Multimodal MRI Analysis of Speech
• Cardiac/Tongue Motion Modeling and Analysis
• Dynamic MR Imaging and Image Analysis
• Functional and Anatomical Atlas
• Behavioral Imaging and Signal Analysis
• Registration, Segmentation, Longitudinal analysis, and Tracking

Link to research page.

Members

Selected Publications

• Xing F, Jin R, Gilbert I, El Fakhri G, Perry J, Sutton B, Woo J. Quantifying Velopharyngeal Motion Variation in Speech Sound Production Using an Audio-Informed Dynamic MRI Atlas. Proc SPIE Int Soc Opt Eng 2023 12464 ():
• Liu X, Xing F, El Fakhri G, Woo J. Memory consistent unsupervised off-the-shelf model adaptation for source-relaxed medical image segmentation. Med Image Anal 2023 83 ():102641
• Liu X, Xing F, Prince JL, Zhuo J, Stone M, Fakhri GE, Woo J. Tagged-MRI Sequence to Audio Synthesis via Self Residual Attention Guided Heterogeneous Translator. Med Image Comput Comput Assist Interv 2022 13436 ():376-386
• Liu X, Xing F, Shusharina N, Lim R, Kuo CJ, El Fakhri G, Woo J. ACT: Semi-supervised Domain-adaptive Medical Image Segmentation with Asymmetric Co-Training. Med Image Comput Comput Assist Interv 2022 13435 ():66-76
• Xing F, Liu X, Reese TG, Stone M, Wedeen VJ, Prince JL, El Fakhri G, Woo J. Measuring Strain in Diffusion-Weighted Data Using Tagged Magnetic Resonance Imaging. Proc SPIE Int Soc Opt Eng 2022 12032
• Liu X, Xing F, El Fakhri G, Woo J. Memory consistent unsupervised off-the-shelf model adaptation for source-relaxed medical image segmentation. Med Image Anal 2022 83 :102641
• Xing F, Liu X, Kuo CJ, El Fakhri G, Woo J. Brain MR Atlas Construction Using Symmetric Deep Neural Inpainting. IEEE J Biomed Health Inform 2022 26 (7):3185-3196
• Liu X, Yoo C, Xing F, Kuo CJ, El Fakhri G, Kang JW, Woo J. Unsupervised Black-Box Model Domain Adaptation for Brain Tumor Segmentation. Front Neurosci 2022 16 ():837646
• Xing F, Jin R, Gilbert IR, Perry JL, Sutton BP, Liu X, El Fakhri G, Shosted RK, Woo J. 4D magnetic resonance imaging atlas construction using temporally aligned audio waveforms in speech. J Acoust Soc Am 2021 150 (5):3500
• Liu X, Xing F, Yang C, Fakhri GE, Woo J. Adapting Off-the-Shelf Source Segmenter for Target Medical Image Segmentation. Med Image Comput Comput Assist Interv 2021 12902 ():549-559
• Liu X, Xing F, Stone M, Zhuo J, Reese T, Prince JL, Fakhri GE, Woo J. Generative Self-training for Cross-domain Unsupervised Tagged-to-Cine MRI Synthesis. Med Image Comput Comput Assist Interv 2021 12903 ():138-148
• Xing F, Jin R, Gilbert IR, Perry JL, Sutton BP, Liu X, El Fakhri G, Shosted RK, Woo J. 4D magnetic resonance imaging atlas construction using temporally aligned audio waveforms in speech. J Acoust Soc Am 2021 150 (5):3500
• Liu X, Xing F, Yang C, Jay Kuo CC, El Fakhri G, Woo J. Symmetric-Constrained Irregular Structure Inpainting for Brain MRI Registration with Tumor Pathology. Brainlesion 2021 12658 ():80-91
• Xing F, Stone M, Prince JL, Liu X, Fakhri GE, Woo J. Floor-of-the-Mouth Muscle Function Analysis Using Dynamic Magnetic Resonance Imaging. Proc SPIE Int Soc Opt Eng 2021 11596 ():
• Woo J, Xing F, Prince JL, Stone M, Gomez AD, Reese TG, Wedeen VJ, El Fakhri G. A deep joint sparse non-negative matrix factorization framework for identifying the common and subject-specific functional units of tongue motion during speech. Med Image Anal 2021 72 ():102131
• Woo J, Xing F, Prince JL, Stone M, Reese TG, Wedeen VJ, El Fakhri G. Identifying the Common and Subject-specific Functional Units of Speech Movements via a Joint Sparse Non-negative Matrix Factorization Framework. Proc SPIE Int Soc Opt Eng 2020; 11313():
  View in: PubMed
• Woo J, Prince JL, Stone M, Xing F, Gomez AD, Green JR, Hartnick CJ, Brady TJ, Reese TG, Wedeen VJ, El Fakhri G. A Sparse Non-Negative Matrix Factorization Framework for Identifying Functional Units of Tongue Behavior From MRI. IEEE Trans Med Imaging 2019; 38(3):730-740
  View in: PubMed
• Woo J, Xing F, Stone M, Green J, Reese TG, Brady TJ, Wedeen VJ, Prince JL, El Fakhri G. Speech Map: A Statistical Multimodal Atlas of 4D Tongue Motion During Speech from Tagged and Cine MR Images. Comput Methods Biomech Biomed Eng Imaging Vis 2019; 7(4):361-373
  View in: PubMed
• Xing F, Stone M, Goldsmith T, Prince JL, El Fakhri G, Woo J. Atlas-Based Tongue Muscle Correlation Analysis From Tagged and High-Resolution Magnetic Resonance Imaging. J. Speech Lang. Hear. Res. 2019; 62(7):2258-2269
  View in: PubMed
• Woo J, Xing F, Prince JL, Stone M, Green JR, Goldsmith T, Reese TG, Wedeen VJ, El Fakhri G. Differentiating post-cancer from healthy tongue muscle coordination patterns during speech using deep learning. J. Acoust. Soc. Am. 2019; 145(5):EL423
  View in: PubMed
• Chang Y, Sharp GC, Li Q, Shih HA, El Fakhri G, Ra JB, Woo J. Subject-specific Brain Tumor Growth Modelling via An Efficient Bayesian Inference Framework. Proc SPIE Int Soc Opt Eng 2018; 10574(): View in: PubMed
• Woo J, Xing F, Lee J, Stone M, Prince JL. A Spatio-Temporal Atlas and Statistical Model of the Tongue During Speech from Cine-MRI. Comput Methods Biomech Biomed Eng Imaging Vis 2018; 6(5):520-531
  View in: PubMed
• Lee E, Xing F, Ahn S, Reese TG, Wang R, Green JR, Atassi N, Wedeen VJ, El Fakhri G, Woo J. Magnetic resonance imaging based anatomical assessment of tongue impairment due to amyotrophic lateral sclerosis: A preliminary study. J. Acoust. Soc. Am. 2018; 143(4):EL248
  View in: PubMed
• Xing F, Prince JL, Stone M, Reese TG, Atassi N, Wedeen VJ, El Fakhri G, Woo J. Strain Map of the Tongue in Normal and ALS Speech Patterns from Tagged and Diffusion MRI. Proc SPIE Int Soc Opt Eng 2018; 10574():
  View in: PubMed
• Xing F, Prince JL, Stone M, Wedeen VJ, Fakhri GE, Woo J. A Four-dimensional Motion Field Atlas of the Tongue from Tagged and Cine Magnetic Resonance Imaging. Proc SPIE Int Soc Opt Eng 2017; 10133():
  View in: PubMed
• Xing F, Woo J, Lee J, Murano EZ, Stone M, Prince JL. Analysis of 3-D Tongue Motion From Tagged and Cine Magnetic Resonance Images. J. Speech Lang. Hear. Res. 2016; 59(3):468-79
  View in: PubMed
• Woo J, Xing F, Lee J, Stone M, Prince JL. Construction of An Unbiased Spatio-Temporal Atlas of the Tongue During Speech. Inf Process Med Imaging 2015; 24():723-32
  View in: PubMed
• Woo J, Lee J, Murano EZ, Xing F, Al-Talib M, Stone M, Prince JL. A High-resolution Atlas and Statistical Model of the Vocal Tract from Structural MRI. Comput Methods Biomech Biomed Eng Imaging Vis ; 3(1):47-60
  View in: PubMed
• Woo J, Stone M, Prince JL. Multimodal registration via mutual information incorporating geometric and spatial context. IEEE Trans Image Process 2015; 24(2):757-69
  View in: PubMed
• Woo J, Xing F, Lee J, Stone M, Prince JL. Determining functional units of tongue motion via graph-regularized sparse non-negative matrix factorization. Med Image Comput Comput Assist Interv 2014; 17(Pt 2):146-53
  View in: PubMed
• Woo J, Stone M, Suo Y, Murano EZ, Prince JL. Tissue-point motion tracking in the tongue from cine MRI and tagged MRI. J. Speech Lang. Hear. Res. 2014; 57(2):S626-36
  View in: PubMed
• Xing F, Woo J, Murano EZ, Lee J, Stone M, Prince JL. 3D tongue motion from tagged and cine MR images. Med Image Comput Comput Assist Interv 2013; 16(Pt 3):41-8
  View in: PubMed
• Woo J, Murano EZ, Stone M, Prince JL. Reconstruction of high-resolution tongue volumes from MRI. IEEE Trans Biomed Eng 2012; 59(12):3511-24
  View in: PubMed
• Woo J, Stone M, Prince JL. Deformable Registration of Multimodal Tongue MR Images. Proc Int Semin Speech Prod 2011; 2011():17-24
  View in: PubMed

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